A9393

Sigma

 

Ampicillin

anhydrous, 96.0-100.5% (anhydrous basis)

Synonym:D-(−)-α-Aminobenzylpenicillin
CAS Number:69-53-4
Linear Formula:C16H19N3O4S
Molecular Weight:349.40
Beilstein Registry Number:1090925
EC Number:200-709-7
MDL number:MFCD00005175
PubChem Substance ID:24891442

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Description

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Biochem/physiol ActionsA β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

Properties

assay96.0-100.5% (anhydrous basis)
mp208 °C (dec.)(lit.)
solubility1 M NH4OH: 50 mg/mL
storage temp.2-8°C

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard CodesXn
Risk Statements36/37/38-42/43
Safety Statements22-26-36/37
WGK Germany2
RTECSXH8350000

References

MerckMerck 13,591
referenceCorp MSDS 1 (1), 247:A / RegBook 1 (2), 2065:H / Sax 6, 201 / Sigma FT-IR 1 (1), 619:A / Structure Index 1, 328:A:3